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  • Sijbom M
  • Büchner FL
  • Saadah NH
  • de Boer MG
  • Numans ME
(2022). Comparing antibiotic prescriptions in primary care between SARS-CoV-2 and influenza: a retrospective observational study. BJGP open, 6(4). 10.3399/BJGPO.2022.0049


Themes: ThemeC , Datasources: Gpdata Hospitaldata

Antibiotics are frequently prescribed during viral respiratory infection episodes in primary care. There is limited information about antibiotic prescription during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in primary care and its association with risk factors for an adverse course.

  • Sijbom M
  • Braun KK
  • Büchner FL
  • van Bodegom-Vos L
  • Hendriks BJC
  • de Boer MGJ
  • Numans ME
  • Lambregts MMC
(2022). Cues to improve antibiotic-allergy registration: A mixed-method study. PloS one, 17(4), e0266473. 10.1371/journal.pone.0266473


Themes: ThemeA ThemeC , Datasources: Gpdata

Approximately 2% of patients in primary care practice and up to 25% of hospital patients are registered as being allergic to an antibiotic. However, up to 90% of these registrations are incorrect, leading to unnecessary prescription of 2nd choice antibiotics with the attendant loss of efficacy, increased toxicity and antibiotic resistance. To improve registration, a better understanding is needed of how incorrect labels are attributed.

  • Sijbom M
  • Büchner FL
  • Saadah NH
  • Numans ME
  • de Boer MGJ
(2023). Determinants of inappropriate antibiotic prescription in primary care in developed countries with general practitioners as gatekeepers: a systematic review and construction of a framework. BMJ open, 13(5), e065006. 10.1136/bmjopen-2022-065006


Themes: ThemeA , Datasources: Hospitaldata

This study aimed to identify determinants of inappropriate antibiotic prescription in primary care in developed countries and to construct a framework with the determinants to help understand which actions can best be targeted to counteract development of antimicrobial resistance (AMR).